The true story of bestselling celebrity biographer (and friend to cats) Lee Israel (Melissa McCarthy), who made her living in the 1970s and '80s profiling the likes of Katherine Hepburn, Tallulah Bankhead, Estee Lauder and journalist Dorothy Kilgallen. When Lee is no longer able to get published because she has fallen out of step with current tastes, she turns her art form to deception, abetted by her loyal friend Jack.